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Dan
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L813/hr
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1st lesson free
- Molecular biology
Learn molecular biology with a pioneer in the field from cutting edge techniques to the broad theories driving discovery.
- Molecular biology
Lesson location
About Dan
I began my neuro-oncology career at UCLA in graduate school working to characterize the molecular biology of patient derived brain tumor cell cultures, delineate the mechanism of resistance to mTOR inhibition, and study differential sensitivity to therapy. As you see in my resume I achieved these goals, delineated a novel pathway of resistance to mTOR inhibition, and published all three studies as a first author.
As a post doctoral scholar at the Sloan Kettering Institute, I joined the Luis Parada lab to study cancer stem cells based on their genetically engineered mouse model. First, we characterized their cells of origin, neural stem cells. Through scRNA-Seq and transcriptomics, I discovered a gene signature for glioblastoma stem cells, and moreover, a cell surface marker, F3, which we used to sort out quiescent glioblastoma stem cells and demonstrate their unique self-renewal capacity (co-first author Study in Developmental Cell).
In 2020, I was recruited by Voyager Therapeutics to help start up the neuro-oncology group. I served as a successful program lead of the vHER2 program, established pre-clinical efficacy models, and developed AAV mediated gene therapy with enhanced Fc modified vectorized antibodies to treat HER2+ breast cancer brain metastasis. I designed, developed, and performed in vivo orthotopic xenograft studies for PK/PD and preclinical pharmacology. I performed scRNA-Seq to delineate the innate immune response to therapy. I led the design of mutating the Fc region to obviate FcRN binding and reduce peripheral levels of our therapeutic antibody to have selective exposure in the brain and reduce the risk of cardiotoxicity. As the project lead, I oversaw the vHER2 program including producing timelines and carrying out oversight of CROs for both mouse and NHP studies (Presentation at SNO/ASCO 2023). I have 4 patents published from this work (WO(concealed information), WO(concealed information), WO(concealed information), WO(concealed information)) including the novel vHER2 therapy, a novel class of BBB penetrant AAV, and 14 more pending patents.
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About the lesson
- Primary
- Lower Secondary
- Senior Secondary
- +7
levels :
Primary
Lower Secondary
Senior Secondary
Post Secondary Education
Higher Education
Adult Education
Master's Degree
Doctorate
MBA
Early Childhood Care & Development
- English
All languages in which the lesson is available :
English
Teaching Method and Techniques
My teaching method is centered around active learning and student engagement. I believe that students learn best when they are actively involved in the learning process. Here are some techniques I use:
Interactive Discussions: Encouraging students to ask questions and participate in discussions to deepen their understanding.
Problem-Solving: Using real-world problems to apply theoretical concepts, which helps in better retention and understanding.
Visual Aids: Utilizing diagrams, charts, and videos to explain complex concepts.
Feedback and Assessment: Providing regular feedback and assessments to track progress and identify areas for improvement.
A Typical Lesson Plan
A typical lesson plan might look like this:
Introduction (5-10 minutes): Briefly review the previous lesson and outline the objectives for the current lesson.
Main Content (30-40 minutes): Present new material using a mix of lectures, visual aids, and interactive discussions.
Practice (20-30 minutes): Engage students in problem-solving activities or group work to apply what they’ve learned.
Review and Q&A (10-15 minutes): Summarize key points and address any questions or concerns.
Homework Assignment: Provide a relevant assignment to reinforce the day’s lesson.
What Sets Me Apart as a Tutor
What sets me apart is my experience as a pioneer in the field, adaptability and personalized approach. I tailor my teaching methods to suit the individual needs and learning styles of my students. Additionally, my background in various subjects allows me to provide a well-rounded educational experience. I also focus on building a positive and encouraging learning environment, which helps students feel more confident and motivated.
Who the Lessons Are For
My lessons are designed for a wide range of students, including:
High School Students: Preparing for exams or needing help with specific subjects.
College Students: Seeking assistance with coursework, projects, or exam preparation.
Adult Learners: Looking to gain new skills or knowledge in a particular area.
Professionals: Wanting to enhance their expertise or prepare for certifications.
Whether you’re a high school student struggling with math, a college student needing help with a research project, or a professional looking to learn a new skill, my lessons are tailored to meet your specific needs and goals.
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Rates
Rate
- L813
Pack prices
- 5h: L4065
- 10h: L8130
free lessons
The first free lesson with Dan will allow you to get to know each other and clearly specify your needs for your next lessons.
- 1hr
online
- L813/h
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